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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FUSIP1 Polyclonal Antibody

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货号 TMAB-06210

Anti-FUSIP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FUSIP1。Anti-FUSIP1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-FUSIP1 Polyclonal Antibody

Anti-FUSIP1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06210

Anti-FUSIP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FUSIP1。Anti-FUSIP1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-FUSIP1 Polyclonal Antibody is a Rabbit antibody targeting FUSIP1. Anti-FUSIP1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus speckle. Cytoplasm.
组织特异性Widely expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FUSIP1 is a member of the Serine/Arginine (SR) family of splicing factors. Members of the SR family all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. SR factors are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Expressed in a variety of tissues with low expression in kidney, liver and heart, FUSIP1 localizes to the cytoplasm and nuclear speckles. In its dephosphorylated form (occurring during M phase of the cell cycle), FUSIP1 functions as a potent general repressor of pre-mRNA splicing and can interact with U1 SnRNP 70. In its phosphorylated form, FUSIP1 interacts with Tra-2∫ and, together, they may cooperate in the regulation of splicing. Four isoforms exist for FUSIP1. In neurons, FUSIP1 isoforms may act to either positively or negatively regulate alternative splicing.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FUSIP1
抗原种属
Human
基因名称
SRSF10
基因ID
10772
蛋白名称
Serine/arginine-rich splicing factor 10
Uniprot ID
O75494
功能
Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator.
化学信息
分子量Theoretical: 31 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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