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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DOK5 Polyclonal Antibody

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货号 TMAB-05280

Anti-DOK5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DOK5。Anti-DOK5 Polyclonal Antibody 可用于 FCM。

Anti-DOK5 Polyclonal Antibody

Anti-DOK5 Polyclonal Antibody

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货号 TMAB-05280

Anti-DOK5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DOK5。Anti-DOK5 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-DOK5 Polyclonal Antibody is a Rabbit antibody targeting DOK5. Anti-DOK5 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
验证活性
The blue histogram is unstained cells (HepG 2).
The Wathet Blue histogram is cells stained with secondary antibody alone. The Orange histogram is cells stained with rabbit IgG isotype control antibody plus secondary antibody.
The green histogram is cells stained with Rabbit Anti-DOK5 antibody (TMAB-05280) plus secondary antibody. 5μg in 100μL 1 X PBS containing 0.5% BSA.
应用FCM
推荐剂量
FCM: 5μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4 and Dok-5 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to Insulin and Insulin-like growth factor-1. The gene encoding human Dok-5 maps to chromosomal location 20q13.2.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DOK5/IRS6
抗原种属
Human
基因名称
DOK5
基因ID
55816
蛋白名称
Docking protein 5
功能
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
化学信息
分子量Theoretical: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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