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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DOK5 Polyclonal Antibody

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货号 TMAB-05280

Anti-DOK5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DOK5。Anti-DOK5 Polyclonal Antibody 可用于 FCM。

Anti-DOK5 Polyclonal Antibody

Anti-DOK5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05280

Anti-DOK5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DOK5。Anti-DOK5 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-DOK5 Polyclonal Antibody is a Rabbit antibody targeting DOK5. Anti-DOK5 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用FCM
推荐剂量
FCM: 5μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4 and Dok-5 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to Insulin and Insulin-like growth factor-1. The gene encoding human Dok-5 maps to chromosomal location 20q13.2.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DOK5/IRS6
抗原种属
Human
基因名称
DOK5
基因ID
55816
蛋白名称
Docking protein 5
功能
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
化学信息
分子量Theoretical: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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