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Anti-Mesothelin Antibody (6G41)
还可以产品编号 TMAY-02493
Anti-Mesothelin Antibody (6G41) 是一种 Mouse 抗体，靶向 Mesothelin。Anti-Mesothelin Antibody (6G41) 可用于 ELISA,IHC-P。
Anti-Mesothelin Antibody (6G41)
Anti-Mesothelin Antibody (6G41)
还可以产品编号 TMAY-02493
Anti-Mesothelin Antibody (6G41) 是一种 Mouse 抗体，靶向 Mesothelin。Anti-Mesothelin Antibody (6G41) 可用于 ELISA,IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Mesothelin Antibody (6G41) is a Mouse antibody targeting Mesothelin. Anti-Mesothelin Antibody (6G41) can be used in ELISA,IHC-P. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 6G41 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human Mesothelin in human ovarian cancer with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human Mesothelin in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | ELISA,IHC-P |
| 推荐剂量 | ELISA: 1:1000-1:2000; IHC-P: 1:30-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Mesothelin / MSLN (rh Mesothelin / MSLN; TMPY-00132; NP_005814.2; Glu296-Gly580). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Mesothelin / MSLN Protein (TMPY-00132) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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