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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ROS1 Antibody (7L404)

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货号 TMAB-12346

Anti-ROS1 Antibody (7L404) 是一种 Mouse 抗体，靶向 ROS1。Anti-ROS1 Antibody (7L404) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ROS1 Antibody (7L404)

Anti-ROS1 Antibody (7L404)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12346

Anti-ROS1 Antibody (7L404) 是一种 Mouse 抗体，靶向 ROS1。Anti-ROS1 Antibody (7L404) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍

生物活性
产品描述
Anti-ROS1 Antibody (7L404) is a Mouse antibody targeting ROS1. Anti-ROS1 Antibody (7L404) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG1, k
克隆号
7L404
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:200-300; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Expressed in brain. Expression is increased in primary gliomas.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human ROS1
抗原种属
Human
基因名称
ROS1
基因ID
6098
蛋白名称
Proto-oncogene tyrosine-protein kinase ROS
Uniprot ID
P08922
功能
Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
化学信息
分子量Theoretical: 258 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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