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Anti-Phospho-Tau (Thr231) Polyclonal Antibody

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Anti-Phospho-Tau (Thr231) Polyclonal Antibody
产品编号 TMAB-01520

Anti-Phospho-Tau (Thr231) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Tau (Thr231)。Anti-Phospho-Tau (Thr231) Polyclonal Antibody 可用于 WB。

Anti-Phospho-Tau (Thr231) Polyclonal Antibody

Anti-Phospho-Tau (Thr231) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-Tau (Thr231) Polyclonal Antibody
产品编号 TMAB-01520

Anti-Phospho-Tau (Thr231) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Tau (Thr231)。Anti-Phospho-Tau (Thr231) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Tau (Thr231) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tau (Thr231). Anti-Phospho-Tau (Thr231) Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit)
验证活性
1. (mouse/tissue) cerebellum lysates probed with p-Tau (Thr231) Polyclonal Antibody, Unconjugated at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:10000 for 60 min at 37˚C.
2. Sample:
Cerebrum (Rat) Lysate at 40 μg
Cerebrum (Mouse) Lysate at 40 μg
Cerebellum (Rat) Lysate at 40 μg
Cerebellum (Mouse) Lysate at 40 μg
Primary: Anti-phospho-Tau (Thr231) (TMAB-01520) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52/79 kDa
Observed band size: 52 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Tau around the phosphorylation site of Thr231
抗原种属
Human
基因ID
Uniprot ID
研究领域
Axon marker,Tangles & Tau,Neurodegenerative disease,Tau
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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