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Anti-Phospho-Tau (Thr231) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Tau (Thr231)。Anti-Phospho-Tau (Thr231) Polyclonal Antibody 可用于 WB。
Anti-Phospho-Tau (Thr231) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Tau (Thr231)。Anti-Phospho-Tau (Thr231) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,975 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-Phospho-Tau (Thr231) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tau (Thr231). Anti-Phospho-Tau (Thr231) Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit) |
验证活性 | 1. (mouse/tissue) cerebellum lysates probed with p-Tau (Thr231) Polyclonal Antibody, Unconjugated at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:10000 for 60 min at 37˚C. 2. Sample: Cerebrum (Rat) Lysate at 40 μg Cerebrum (Mouse) Lysate at 40 μg Cerebellum (Rat) Lysate at 40 μg Cerebellum (Mouse) Lysate at 40 μg Primary: Anti-phospho-Tau (Thr231) (TMAB-01520) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52/79 kDa Observed band size: 52 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
免疫原 | KLH conjugated Synthesised phosphopeptide: human Tau around the phosphorylation site of Thr231 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Axon marker,Tangles & Tau,Neurodegenerative disease,Tau |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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