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IgG2a Protein, Rat, Recombinant

IgG2a Protein, Rat, Recombinant

产品编号 TMPJ-00893
别名: Ig γ-2A chain C region, Ig gamma-2A chain C region, Igg-2a

Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

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IgG2a Protein, Rat, Recombinant
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 700 5日内发货
500 μg ¥ 4,740 5日内发货
1 mg ¥ 7,510 5日内发货
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产品目录号及名称: IgG2a Protein, Rat, Recombinant (TMPJ-00893)
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产品描述 Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.
种属 Rat
表达系统 Human Cells
标签 None
蛋白编号 P20760
别名 Ig γ-2A chain C region, Ig gamma-2A chain C region, Igg-2a
氨基酸序列 Val98-Lys322
蛋白构建 Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 30-35 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.5.
复溶方法 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
存储

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

运输方式

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

研究背景 Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

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Keywords

IgG2a Protein, Rat, Recombinant Ig γ-2A chain C region Ig gamma-2A chain C region Igg-2a recombinant recombinant-proteins proteins protein

 

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