购物车
- 全部删除
- 您的购物车当前为空
Anti-CD30/TNFRSF8 Antibody (4I379) 是一种 Mouse 抗体,靶向 CD30/TNFRSF8。Anti-CD30/TNFRSF8 Antibody (4I379) 可用于 ELISA。
Anti-CD30/TNFRSF8 Antibody (4I379) 是一种 Mouse 抗体,靶向 CD30/TNFRSF8。Anti-CD30/TNFRSF8 Antibody (4I379) 可用于 ELISA。
产品描述 | Anti-CD30/TNFRSF8 Antibody (4I379) is a Mouse antibody targeting CD30/TNFRSF8. Anti-CD30/TNFRSF8 Antibody (4I379) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 4I379 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD30 / TNFRSF8 (rh CD30 / TNFRSF8; TMPY-01827; NP_001234.2; Met 1-Lys 379). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD30 / TNFRSF8 protein (TMPY-01827) |
抗原种属 | Human |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容