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Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) 是一种 HRP-conjugated Mouse 抗体,靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) 可用于 ELISA。
Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) 是一种 HRP-conjugated Mouse 抗体,靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) 可用于 ELISA。
产品描述 | Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) is a HRP-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 3X829 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 0.1-1 μg/mL |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; TMPY-01873; AAA61153.1; Cys89-Phe 760). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
偶联 | HRP |
其他可选修饰符 | Unconjugated |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human Transferrin Receptor / TFRC / CD71 protein (TMPY-01873) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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