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顶部生物活性储存和溶解信息计算器

Anti-Survivin Antibody (2N702)

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Anti-Survivin Antibody (2N702)
产品编号 TMAC-03921
别名 IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4

Anti-Survivin Antibody (2N702) 是一种 Rabbit 抗体，靶向 Survivin。Anti-Survivin Antibody (2N702) 可用于 WB,IHC,IP。

Anti-Survivin Antibody (2N702)

Anti-Survivin Antibody (2N702)

Rating icon 还可以
Anti-Survivin Antibody (2N702)
产品编号 TMAC-03921 别名 IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4

Anti-Survivin Antibody (2N702) 是一种 Rabbit 抗体，靶向 Survivin。Anti-Survivin Antibody (2N702) 可用于 WB,IHC,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Survivin Antibody (2N702) is a Rabbit antibody targeting Survivin. Anti-Survivin Antibody (2N702) can be used in WB,IHC,IP.
别名IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4
Ig Type
IgG
交叉反应
Mouse,Rat
验证活性
1. Western blot analysis of Survivin on different lysates using anti-Survivin antibody at 1/1,000 dilution. Positive control: Lane 1: L929, Lane 2: F9.
2. Immunohistochemical analysis of paraffin-embedded rat spleen tissue using anti-Survivin antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Survivin antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Survivin antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-Survivin antibody. Counter stained with hematoxylin.
应用
WB
IHC
IP
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The baculovirus protein p35 inhibits virally-induced apoptosis of invertebrate and mammalian cells and may function to impair the clearing of virally infected cells by the immune system of the host. This is accomplished at least in part by the ability of p35 to block both TNF- and FAS-mediated apoptosis through the inhibition of the ICE family of serine proteases. Two mammalian homologs of baculovirus p35, referred to as inhibitor of apoptosis protein (IAP) 1 and 2, share an amino-terminal baculovirus IAP repeat (BIR) motif and a carboxy-terminal RING finger. Although the c-IAPs do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. Additional IAP family members include ILP (for IAP-like protein) and survivin. ILP inhibits activated caspase-3, leading to the resistance of FAS-mediated apoptosis. Survivin (also designated TIAP) is expressed during the G2/M phase of the cell cycle and associates with microtubules of the mitotic spindle. Increased caspase-3 activity is detected when a disruption of survivin-microtubule interactions occurs.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
化学信息
分子量Theoretical: 16 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

IAP-4IAP 4EPR1EPR 1BIRC-5BIRC 5API-4API 4

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