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LR3-IGF-1 Protein, Mouse, Recombinant (His)

Synonyms: somatomedin-C, Somatomedin C, Insulin-like growth factor I, insulin-like growth factor 1, IGF-1, IGF1
货号 TMPJ-00781 一键复制产品信息
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Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.

LR3-IGF-1 Protein, Mouse, Recombinant (His)

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货号 TMPJ-00781

别名 somatomedin-C, Somatomedin C, Insulin-like growth factor I, insulin-like growth factor 1, IGF-1, IGF1

Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.

LR3-IGF-1 Protein, Mouse, Recombinant (His)
其他形式的 “LR3-IGF-1 Protein, Mouse, Recombinant (His)”:
规格价格库存数量
5 μg
¥ 148
6-8日内发货
10 μg
¥ 220
6-8日内发货
20 μg
¥ 276
5日内发货
50 μg
¥ 380
5日内发货
100 μg
¥ 743
5日内发货
1 mg
¥ 5,530
5日内发货
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选择批次:
纯度: Greater than 95% as determined by reducing SDS-PAGE.
颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南

产品介绍


生物活性
产品描述
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.
种属
Mouse
表达系统
E. coli
标签
C-6xHis
蛋白编号P05017
氨基酸序列
Gly49-Ala118
蛋白构建
Gly49-Ala118
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液
Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM NaAc, pH 4.5.
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
somatomedin-C, Somatomedin C, Insulin-like growth factor I, insulin-like growth factor 1, IGF-1, IGF1
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量12 KDa (reducing condition)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

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