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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HRH3 Polyclonal Antibody 3

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货号 TMAB-07293

Anti-HRH3 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 HRH3。Anti-HRH3 Polyclonal Antibody 3 可用于 WB。

Anti-HRH3 Polyclonal Antibody 3

Anti-HRH3 Polyclonal Antibody 3

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Rating icon 还可以
货号 TMAB-07293

Anti-HRH3 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 HRH3。Anti-HRH3 Polyclonal Antibody 3 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-HRH3 Polyclonal Antibody 3 is a Rabbit antibody targeting HRH3. Anti-HRH3 Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human HRH3
抗原种属
Human
基因名称
HRH3
基因ID
11255
蛋白名称
Histamine H3 receptor
Uniprot ID
Q9Y5N1
功能
The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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