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Anti-DPP4/CD26 Antibody (5T73) 是一种 Rabbit 抗体,靶向 DPP4/CD26。Anti-DPP4/CD26 Antibody (5T73) 可用于 WB,ICC/IF,IHC,FCM。
Anti-DPP4/CD26 Antibody (5T73) 是一种 Rabbit 抗体,靶向 DPP4/CD26。Anti-DPP4/CD26 Antibody (5T73) 可用于 WB,ICC/IF,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-DPP4/CD26 Antibody (5T73) is a Rabbit antibody targeting DPP4/CD26. Anti-DPP4/CD26 Antibody (5T73) can be used in WB,ICC/IF,IHC,FCM. |
别名 | dipeptidylpeptidase 4 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-100; ICC/IF: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | CD26 (dipeptidylpeptidase 4, adenosine deaminase complexing protein 2, ADABP, ADCP2, DPPIV, TP103) is a membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. CD26 has an essential role in immune regulation as a T cell activation molecule and a regulator of chemokine function. CD26 associates with CXCR4 and gp120 and may influence the pathophysiology of HIV infection. Adenosine deaminase (ADA) colocalizing with adenosine receptors on dendritic cells are able to interact with CD26 expressed on lymphocytes. This costimulatory signal in the immunological synapse leads to an increase in the production of the T helper 1 and proinflammatory cytokines IFN-gamma, TNF-alpha, and IL-6. CD26 plays a role in the pathogenesis and behavior of human cancers, including solid tumors and hematological malignancies. CD26-caveolin-1 interaction plays a role in the up-regulation of CD86 on TT-loaded monocytes and subsequent engagement with CD28 on T cells, leading to antigen-specific T cell activation. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 110 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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