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Anti-DPP4/CD26 Antibody (5T73)

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Anti-DPP4/CD26 Antibody (5T73)
产品编号 TMAC-00686
别名 dipeptidylpeptidase 4

Anti-DPP4/CD26 Antibody (5T73) 是一种 Rabbit 抗体,靶向 DPP4/CD26。Anti-DPP4/CD26 Antibody (5T73) 可用于 WB,ICC/IF,IHC,FCM。

Anti-DPP4/CD26 Antibody (5T73)

Anti-DPP4/CD26 Antibody (5T73)

Rating icon 还可以
Anti-DPP4/CD26 Antibody (5T73)
产品编号 TMAC-00686 别名 dipeptidylpeptidase 4

Anti-DPP4/CD26 Antibody (5T73) 是一种 Rabbit 抗体,靶向 DPP4/CD26。Anti-DPP4/CD26 Antibody (5T73) 可用于 WB,ICC/IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-DPP4/CD26 Antibody (5T73) is a Rabbit antibody targeting DPP4/CD26. Anti-DPP4/CD26 Antibody (5T73) can be used in WB,ICC/IF,IHC,FCM.
别名dipeptidylpeptidase 4
Ig Type
IgG
交叉反应
Human,Mouse,Rat
应用
推荐剂量
WB: 1:500-2000; IHC: 1:50-100; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景CD26 (dipeptidylpeptidase 4, adenosine deaminase complexing protein 2, ADABP, ADCP2, DPPIV, TP103) is a membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. CD26 has an essential role in immune regulation as a T cell activation molecule and a regulator of chemokine function. CD26 associates with CXCR4 and gp120 and may influence the pathophysiology of HIV infection. Adenosine deaminase (ADA) colocalizing with adenosine receptors on dendritic cells are able to interact with CD26 expressed on lymphocytes. This costimulatory signal in the immunological synapse leads to an increase in the production of the T helper 1 and proinflammatory cytokines IFN-gamma, TNF-alpha, and IL-6. CD26 plays a role in the pathogenesis and behavior of human cancers, including solid tumors and hematological malignancies. CD26-caveolin-1 interaction plays a role in the up-regulation of CD86 on TT-loaded monocytes and subsequent engagement with CD28 on T cells, leading to antigen-specific T cell activation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 110 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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