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Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody

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Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody
产品编号 TMAC-00274
别名 p-ARRB1 (Ser412), p-ARRB1 (S412), ARRB1 (p-Ser412), ARRB1 (p-S412)

Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-ARRB1 (Ser412)。Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody

Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody
产品编号 TMAC-00274 别名 p-ARRB1 (Ser412), p-ARRB1 (S412), ARRB1 (p-Ser412), ARRB1 (p-S412)

Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-ARRB1 (Ser412)。Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ARRB1 (Ser412). Anti-Phospho-ARRB1 (Ser412) Polyclonal Antibody can be used in WB,IHC.
别名p-ARRB1 (Ser412), p-ARRB1 (S412), ARRB1 (p-Ser412), ARRB1 (p-S412)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from COS7 cells treated with Etoposide using Arrestin 1 (Phospho-Ser412) Antibody TMAC-00274. The lane on the right is treated with the antigen-specific peptide.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Arrestin 1 (Phospho-Ser412) antibody TMAC-00274 (left) or the same antibody preincubated with blocking peptide (right).
应用
WB
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Serine 412 (T-G-S(p)-P-Q) derived from Human Arrestin 1
抗原种属
human
Uniprot ID
P49407
化学信息
分子量Actual: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pARRB1 (Ser412)pARRB1 (S412)ARRB1 (pSer412)ARRB1 (pS412)ARRB1 (phospho-Ser412)ARRB1 (phospho-S412)

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