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Anti-ADAMTS4 Polyclonal Antibody

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Anti-ADAMTS4 Polyclonal Antibody
产品编号 TMAB-00056

Anti-ADAMTS4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADAMTS4。Anti-ADAMTS4 Polyclonal Antibody 可用于 WB。

Anti-ADAMTS4 Polyclonal Antibody

Anti-ADAMTS4 Polyclonal Antibody

Rating icon 还可以
Anti-ADAMTS4 Polyclonal Antibody
产品编号 TMAB-00056

Anti-ADAMTS4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADAMTS4。Anti-ADAMTS4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADAMTS4 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS4. Anti-ADAMTS4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Cow,Rabbit,Sheep)
验证活性
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Lane 3: Human A549 cell lysates
Primary: Anti-ADAMTS4 (TMAB-00056) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 90 kDa
Observed band size: 100 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. extracellular space. extracellular matrix.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADAMTS4
抗原种属
Human
基因ID
Uniprot ID
研究领域
MMP,ADAM Protein Family,ADAM TS,ADAM protein family
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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