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Anti-ADAMTS4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADAMTS4。Anti-ADAMTS4 Polyclonal Antibody 可用于 WB。
Anti-ADAMTS4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADAMTS4。Anti-ADAMTS4 Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,170 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,790 | 5日内发货 |
产品描述 | Anti-ADAMTS4 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS4. Anti-ADAMTS4 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat (predicted:Cow,Rabbit,Sheep) |
验证活性 | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Human A549 cell lysates Primary: Anti-ADAMTS4 (TMAB-00056) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kDa Observed band size: 100 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Secreted. extracellular space. extracellular matrix. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
免疫原 | KLH conjugated synthetic peptide: human ADAMTS4 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | MMP,ADAM Protein Family,ADAM TS,ADAM protein family |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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