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Anti-ESAM Antibody-FITC (4F225)

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Anti-ESAM Antibody-FITC (4F225)
产品编号 TMAY-00424F
别名 endothelial cell adhesion molecule

Anti-ESAM Antibody-FITC (4F225) 是一种 FITC-conjugated Rabbit 抗体，靶向 ESAM。Anti-ESAM Antibody-FITC (4F225) 可用于 FCM。

Anti-ESAM Antibody-FITC (4F225)
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Anti-ESAM Antibody-FITC (4F225)

Rating icon 还可以
Anti-ESAM Antibody-FITC (4F225)
产品编号 TMAY-00424F 别名 endothelial cell adhesion molecule

Anti-ESAM Antibody-FITC (4F225) 是一种 FITC-conjugated Rabbit 抗体，靶向 ESAM。Anti-ESAM Antibody-FITC (4F225) 可用于 FCM。

规格价格库存数量
25 T
¥ 880
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100 T
¥ 1,795
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产品介绍

生物活性
产品描述
Anti-ESAM Antibody-FITC (4F225) is a FITC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-FITC (4F225) can be used in FCM.
别名endothelial cell adhesion molecule
Ig Type
Rabbit IgG
克隆号
4F225
交叉反应
Human
验证活性
Profile of anti-ESAM reactivity on HUVEC cells analyzed by flow cytometry.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ESAM (rh ESAM; TMPY-01312; NP_620411.2; Met 1-Ala 248) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human ESAM protein (TMPY-01312)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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