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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CYP46 Polyclonal Antibody

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货号 TMAB-04899

Anti-CYP46 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP46。Anti-CYP46 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CYP46 Polyclonal Antibody

Anti-CYP46 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04899

Anti-CYP46 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP46。Anti-CYP46 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CYP46 Polyclonal Antibody is a Rabbit antibody targeting CYP46. Anti-CYP46 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
组织特异性Expressed in brain. The mRNA was broadly distributed with higher levels in gray matter zones and lower levels in regions rich in white matter. Not detected in fetal sample but its expression increases linearly with age.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain. Cyp46 is also known as 24S-cholesterol hydroxylase.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CYP46
抗原种属
Human
基因名称
CYP46A1
基因ID
10858
蛋白名称
Cholesterol 24-hydroxylase
Uniprot ID
Q9Y6A2
功能
Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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