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Anti-CYP3A4 Antibody (6F122) 是一种 Rabbit 抗体,靶向 CYP3A4。Anti-CYP3A4 Antibody (6F122) 可用于 WB,IHC,IP。
Anti-CYP3A4 Antibody (6F122) 是一种 Rabbit 抗体,靶向 CYP3A4。Anti-CYP3A4 Antibody (6F122) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-CYP3A4 Antibody (6F122) is a Rabbit antibody targeting CYP3A4. Anti-CYP3A4 Antibody (6F122) can be used in WB,IHC,IP. |
别名 | sulfoxide-forming, Quinine 3-monooxygenase, Nifedipine oxidase, Cytochrome P450-PCN1, Cytochrome P450 NF-25, Cytochrome P450 HLp, Cytochrome P450 3A4, Cytochrome P450 3A3, CYPIIIA4, CYPIIIA3, CYP3A3, Cholesterol 25-hydroxylase, Albendazole sulfoxidase, Albendazole monooxygenase, 1,8-cineole 2-exo-monooxygenase, 1,4-cineole 2-exo-monooxygenase |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of Cytochrome P450 3A4 on human liver tissue lysate using anti-Cytochrome P450 3A4 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cytochrome P450 3A4 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | CYP3A, the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of the clinical test & lt; RTI ID = 0.0 & gt; (cYP3A) genes encode monooxygenases-enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A family members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster maps to gene locus 7q22.1 and consists of four genes (CYP3A4, CYP3A5, CYP3A7 and CYP3A43) and two pseudogenes ( CYP3A4 is abundant in the endoplasmic reticulum of liver cells and upper intestinal enterocytes. CYP3A4 expression is isducible by glucocorticoids pharmacological agents. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 57 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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