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Anti-CD30/TNFRSF8 Antibody-APC (9U146)
还可以产品编号 TMAY-01164A
Anti-CD30/TNFRSF8 Antibody-APC (9U146) 是一种 APC-conjugated Rabbit 抗体，靶向 CD30/TNFRSF8。Anti-CD30/TNFRSF8 Antibody-APC (9U146) 可用于 FCM。
Anti-CD30/TNFRSF8 Antibody-APC (9U146)
Anti-CD30/TNFRSF8 Antibody-APC (9U146)
还可以产品编号 TMAY-01164A
Anti-CD30/TNFRSF8 Antibody-APC (9U146) 是一种 APC-conjugated Rabbit 抗体，靶向 CD30/TNFRSF8。Anti-CD30/TNFRSF8 Antibody-APC (9U146) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-CD30/TNFRSF8 Antibody-APC (9U146) is a APC-conjugated Rabbit antibody targeting CD30/TNFRSF8. Anti-CD30/TNFRSF8 Antibody-APC (9U146) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9U146 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human TNFRSF8(CD30) expression on K562 cells. Cells were stained with APC-conjugated anti-Human TNFRSF8(CD30). The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD30 / TNFRSF8 (rh CD30 / TNFRSF8; TMPY-01827; NP_001234.2; Met1-Lys379) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | APC |
| 其他可选修饰符 | PE |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human CD30 / TNFRSF8 protein (TMPY-01827) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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