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Anti-ST6GAL1 Antibody (4P675) 是一种 Rabbit 抗体,靶向 ST6GAL1。Anti-ST6GAL1 Antibody (4P675) 可用于 IHC-P。
Anti-ST6GAL1 Antibody (4P675) 是一种 Rabbit 抗体,靶向 ST6GAL1。Anti-ST6GAL1 Antibody (4P675) 可用于 IHC-P。
产品描述 | Anti-ST6GAL1 Antibody (4P675) is a Rabbit antibody targeting ST6GAL1. Anti-ST6GAL1 Antibody (4P675) can be used in IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4P675 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human ST6GAL1 in human prostate with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium. 2. Immunochemical staining of human ST6GAL1 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:100-1:500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ST6GAL1 / ST6GAL-I (rh ST6GAL1 / ST6GAL-I; TMPY-02093; P15907; Lys27-Cys406). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein that belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally found in the Golgi but can be proteolytically processed to a soluble form. It is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. β-Galactoside α2,6-sialyltransferases ST6GAL1 and ST6GAL2 are the two unique members of the ST6GAL family described in higher vertebrates. ST6GAL1 / SIAT1 transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ST6GAL1 / ST6GAL-I protein (TMPY-02093) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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