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Cefsulodin sodium

Name: Cefsulodin sodium
Brand: TargetMol
SKU: T0827
Price: 298 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.3%

货号 T0827Cas号 52152-93-9

别名 头孢磺啶钠, Sulcephalosporin, Cefsulodine sodium

Cefsulodin sodium (Sulcephalosporin) 是β内酰胺抗生素，对缘脓杆菌和肠杆菌有活性。

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Cefsulodin sodium

一键复制产品信息

很棒

纯度: 99.3%

货号 T0827 别名 头孢磺啶钠, Sulcephalosporin, Cefsulodine sodiumCas号 52152-93-9

Cefsulodin sodium (Sulcephalosporin) 是β内酰胺抗生素，对缘脓杆菌和肠杆菌有活性。

规格	价格	库存
25 mg	¥ 298	现货
50 mg	¥ 428	现货
100 mg	¥ 622	现货
200 mg	¥ 839	现货
500 mg	¥ 1,390	现货
1 mL x 10 mM (in DMSO)	¥ 683	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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纯度: 98.48%

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COA HPLC HNMR 产品操作手册

产品介绍

Cefsulodin sodium AI Summary

Cefsulodin sodium exhibits significant bioactivity across a range of biological targets, demonstrating diverse inhibitory effects. It exerts inhibitory activity on human Jumonji Domain Containing 2E (JMJD2E), MLL CXXC domain-DNA interaction, Tyrosyl-DNA Phosphodiesterase (TDP1), Tau fibril formation, DNA Polymerase Beta, and several other molecular targets including enzymes and proteins involved in DNA repair, epigenetic regulation, and cellular transport processes. The compound's potency varies widely, from 199.5 nM to 56234.1 nM, depending on the specific target. Additionally, Cefsulodin sodium shows a high level of inhibition (91.84% and 101.2%) in the sodium fluorescein uptake assay in OATP1B1- and OATP1B3-transfected CHO cells at a concentration of 10 µM, suggesting interference with sodium fluorescein transport. In the context of infectious diseases, Cefsulodin sodium inhibits Mycobacterium tuberculosis PTPB with an IC50 value of 16000.0 nM. It also exhibits trypanocidal activity against Trypanosoma cruzi, the causative agent of Chagas disease, displaying moderate activity against the INC-5 strain (14%) and strong activity against the NINOA strain (87%) at 50 µg/mL, with an LC50 value of 16.6 µg/mL against the NINOA strain. Moreover, Cefsulodin sodium shows activity against SARS-CoV-2 in Vero E6 cells, reducing cell viability with an inhibition index of 0.2889 after 72 hours at a MOI of 0.002, indicating potential antiviral properties. Overall, Cefsulodin sodium is a bioactive molecule with inhibitory effects on a variety of biological targets, making it a notable candidate for further investigation in multiple therapeutic areas..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic.
靶点活性	mPTPB:16 μM
别名	头孢磺啶钠, Sulcephalosporin, Cefsulodine sodium

化学信息

分子量	554.52
分子式	C₂₂H₁₉N₄NaO₈S₂
CAS No.	52152-93-9
Smiles	[Na+].NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@@H](c2ccccc2)S([O-])(=O)=O)C3=O)C([O-])=O)cc1
密度	no data available

储存&溶解度

存储

store at low temperature,store under nitrogen | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 55 mg/mL (99.18 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.61 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8034 mL	9.0168 mL	18.0336 mL	90.1681 mL
5 mM	0.3607 mL	1.8034 mL	3.6067 mL	18.0336 mL
10 mM	0.1803 mL	0.9017 mL	1.8034 mL	9.0168 mL
20 mM	0.0902 mL	0.4508 mL	0.9017 mL	4.5084 mL
50 mM	0.0361 mL	0.1803 mL	0.3607 mL	1.8034 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。