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别名 p-IRE1 (Ser724), p-IRE1 (S724), IRE1P, IRE1a, IRE1 (p-Ser724), IRE1 (p-S724), IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1
Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IRE1 (Ser724)。Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody 可用于 WB。
Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IRE1 (Ser724)。Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRE1 (Ser724). Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody can be used in WB. |
| 别名 | p-IRE1 (Ser724), p-IRE1 (S724), IRE1P, IRE1a, IRE1 (p-Ser724), IRE1 (p-S724), IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1 |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Pig,Cow,Horse,Sheep) |
| 验证活性 | Sample: Lane 1: Human 293T cell lysates Lane 2: Human DU145 cell lysates Lane 3: Human HeLa cell lysates Lane 4: Human Jurkat cell lysates Primary: Anti-phospho-IRE1 (Ser724) (TMAB-01432) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 107 kDa Observed band size: 130 kDa ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
| 组织特异性 | Ubiquitously expressed. High levels observed in pancreatic tissue. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human IRE1 around the phosphorylation site of Ser724 |
| 抗原种属 | Human |
| 基因名称 | ERN1 |
| 基因ID | |
| 蛋白名称 | Serine/threonine-protein kinase/endoribonuclease IRE1 |
| Uniprot ID | |
| 研究领域 | Other Kinases |
| 功能 | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| 分子量 | Theoretical: 107 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |