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Anti-Phospho-HDAC5 (Ser498) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HDAC5 (Ser498)。Anti-Phospho-HDAC5 (Ser498) Polyclonal Antibody 可用于 WB,IHC,IF。
Anti-Phospho-HDAC5 (Ser498) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HDAC5 (Ser498)。Anti-Phospho-HDAC5 (Ser498) Polyclonal Antibody 可用于 WB,IHC,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-HDAC5 (Ser498) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC5 (Ser498). Anti-Phospho-HDAC5 (Ser498) Polyclonal Antibody can be used in WB,IHC,IF. |
别名 | p-HDAC5 (Ser498), p-HDAC5 (S498), HDAC5 (p-Ser498), HDAC5 (p-S498) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western Blot analysis of VEC cells using Phospho-HDAC5 (S498) Polyclonal Antibody diluted at 1:500. 2. Western blot analysis of lysates from Jurkat cells, using HDAC5 (Phospho-Ser498) Antibody. The lane on the right is blocked with the phospho peptide. 3. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HDAC5 (Phospho-Ser498) Antibody. The picture on the right is blocked with the phospho peptide. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:100-300; IF: 1:200-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human HDAC5 around the phosphorylation site of Ser498 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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