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Anti-PDCD4 Polyclonal Antibody

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货号 TMAB-10099

Anti-PDCD4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PDCD4。Anti-PDCD4 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

Anti-PDCD4 Polyclonal Antibody

Anti-PDCD4 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10099

Anti-PDCD4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PDCD4。Anti-PDCD4 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
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产品介绍


生物活性
产品描述
Anti-PDCD4 Polyclonal Antibody is a Rabbit antibody targeting PDCD4. Anti-PDCD4 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Ig Type
IgG
反应种属
Human (predicted:Mouse)
应用WBIHC-PIHC-FrIFELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm. Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457. Exported from the nucleus in the absence of serum.
组织特异性Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
抗原信息
免疫原
Recombinant Protein: human PDCD4
抗原种属
Human
基因名称
PDCD4
基因ID
蛋白名称
Programmed cell death protein 4
Uniprot ID
功能
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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