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Anti-KAT3A/CBP Polyclonal Antibody 2

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货号 TMAB-07902

Anti-KAT3A/CBP Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 KAT3A/CBP。Anti-KAT3A/CBP Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-KAT3A/CBP Polyclonal Antibody 2

Anti-KAT3A/CBP Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-07902

Anti-KAT3A/CBP Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 KAT3A/CBP。Anti-KAT3A/CBP Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-KAT3A/CBP Polyclonal Antibody 2 is a Rabbit antibody targeting KAT3A/CBP. Anti-KAT3A/CBP Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Recruited to nuclear bodies by SS18L1/CREST. In the presence of ALX1 relocalizes from the cytoplasm to the nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009].
抗原信息
免疫原
KLH conjugated synthetic peptide: human KAT3A/CBP
抗原种属
Human
基因名称
CREBBP
基因ID
1387
蛋白名称
CREB-binding protein
Uniprot ID
Q92793
功能
Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.
化学信息
分子量Theoretical: 265 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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