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Anti-SETD7 Antibody (8B368)
还可以产品编号 TMAY-01753
Anti-SETD7 Antibody (8B368) 是一种 Mouse 抗体，靶向 SETD7。Anti-SETD7 Antibody (8B368) 可用于 WB。
Anti-SETD7 Antibody (8B368)
Anti-SETD7 Antibody (8B368)
还可以产品编号 TMAY-01753
Anti-SETD7 Antibody (8B368) 是一种 Mouse 抗体，靶向 SETD7。Anti-SETD7 Antibody (8B368) 可用于 WB。
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偶联与修饰
抗原信息
| 产品描述 | Anti-SETD7 Antibody (8B368) is a Mouse antibody targeting SETD7. Anti-SETD7 Antibody (8B368) can be used in WB. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8B368 |
| 交叉反应 | Human |
| 验证活性 | Anti-SETD7 mouse monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell Lysate. -Lane B: MCF7 Whole Cell Lysate. -Lane C: NIH3T3 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:41 kDa. -Observed band size:53 kDa(We are unsure as to the identity of these extra bands.) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SETD7 / SET7 / 9 (rh SETD7 / SET7 / 9; TMPY-01229; NP_085151.1; Asp2-Lys366). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine methyltransferase family and SET7 subfamily. SETD7 is widely expressed and expressed in pancreatic islets. SETD7 contains three MORN repeats and one SET domain. SETD7 plays a central role in the transcriptional activation of genes such as collagenase or insulin. As a protein lysine methyltransferase (PKMT), SETD7 also has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF1, and possibly TAF7 by recognizing and binding in substrate proteins. The mono-methyltransferase activity of SETD7 is achieved by disrupting the formation at near-attack conformations for the dimethylation reaction. SETD7 is also a novel coactivator of NF-kappaB and plays a role in inflammation and diabetes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human SETD7 / SET7 / 9 protein (TMPY-01229) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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