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Anti-LMAN2 Antibody (5D538)

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Anti-LMAN2 Antibody (5D538)
产品编号 TMAY-02355
别名 VIP36, lectin, mannose binding 2, GP36B, C5orf8

Anti-LMAN2 Antibody (5D538) 是一种 Mouse 抗体,靶向 LMAN2。Anti-LMAN2 Antibody (5D538) 可用于 ELISA(Cap)。

Anti-LMAN2 Antibody (5D538)
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Anti-LMAN2 Antibody (5D538)

Rating icon 还可以
Anti-LMAN2 Antibody (5D538)
产品编号 TMAY-02355 别名 VIP36, lectin, mannose binding 2, GP36B, C5orf8

Anti-LMAN2 Antibody (5D538) 是一种 Mouse 抗体,靶向 LMAN2。Anti-LMAN2 Antibody (5D538) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 590
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100 μL
¥ 1,679
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产品介绍

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产品描述
Anti-LMAN2 Antibody (5D538) is a Mouse antibody targeting LMAN2. Anti-LMAN2 Antibody (5D538) can be used in ELISA(Cap).
别名VIP36, lectin, mannose binding 2, GP36B, C5orf8
Ig Type
Mouse IgG2b
克隆号
5D538
交叉反应
Human
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LMAN2 (rh LMAN2; TMPY-02419; Q12907; Asp45-Arg322). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景LMAN2 (Lectin, Mannose Binding 2, also known as VIP36) is a Protein Coding gene. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus, and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking, and quality control. The L-type lectin LMAN2 appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport along the exosomal pathway. This may occur due to interference with the adaptor protein GGA1-mediated trans-Golgi network-to-endosome transport of GPRC5B. A Golgi-traversing pathway for the exosomal release of the cargo protein GPRC5B in which CD2AP facilitates the entry and LMAN2 impedes the exit of the flux, respectively.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human LMAN2 Protein (TMPY-02419)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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