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Anti-CD16/FCGR3 Antibody-FITC (3F748) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Antibody-FITC (3F748) 可用于 FCM。
Anti-CD16/FCGR3 Antibody-FITC (3F748) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Antibody-FITC (3F748) 可用于 FCM。
产品描述 | Anti-CD16/FCGR3 Antibody-FITC (3F748) is a FITC-conjugated Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-FITC (3F748) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3F748 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CD16 expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human CD16. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD16a/Fc gamma RIIIa (rh CD16a/Fc gamma RIIIa; TMPY-00763; P08637-1; Met1-Gln208,176F) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
偶联 | FITC |
其他可选修饰符 | Unconjugated |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human CD16a/Fc gamma RIIIa Protein (TMPY-00763) |
抗原种属 | Human |
研究领域 | Fc Receptors |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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