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Anti-IL-T3 Antibody (4M315) 是一种 Mouse 抗体,靶向 IL-T3。Anti-IL-T3 Antibody (4M315) 可用于 FCM。
Anti-IL-T3 Antibody (4M315) 是一种 Mouse 抗体,靶向 IL-T3。Anti-IL-T3 Antibody (4M315) 可用于 FCM。
产品描述 | Anti-IL-T3 Antibody (4M315) is a Mouse antibody targeting IL-T3. Anti-IL-T3 Antibody (4M315) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 4M315 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human LILRB4(CD85k) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB4(CD85k), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB4/CD85k/ILT3 (rh LILRB4/CD85k/ILT3; TMPY-04650; NP_001265357.2; Met1-Glu259). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases. The LILRB4 is a central inhibitory receptor in Uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface. |
偶联 | Unconjugated |
其他可选修饰符 | APC/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human LILRB4/CD85k/ILT3 Protein (TMPY-04650) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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