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Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487)
还可以产品编号 TMAY-01266
Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487) 是一种 Rabbit 抗体，靶向 TNFR1/CD120a/TNFRSF1A。Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487) 可用于 ICC/IF。
Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487)
Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487)
还可以产品编号 TMAY-01266
Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487) 是一种 Rabbit 抗体，靶向 TNFR1/CD120a/TNFRSF1A。Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487) 可用于 ICC/IF。
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抗原信息
| 产品描述 | Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487) is a Rabbit antibody targeting TNFR1/CD120a/TNFRSF1A. Anti-TNFR1/CD120a/TNFRSF1A Antibody (6Q487) can be used in ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6Q487 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of Human TNFRI in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human TNFRI monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm. |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TNFR1 / CD120a / TNFRSF1A (rh TNFR1 / CD120a / TNFRSF1A; TMPY-01459; NP_001056.1; Met1-Thr211). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein (TMPY-01459) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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