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Anti-Phospho-Cbl-c (Tyr700) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Cbl-c (Tyr700)。Anti-Phospho-Cbl-c (Tyr700) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。
Anti-Phospho-Cbl-c (Tyr700) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Cbl-c (Tyr700)。Anti-Phospho-Cbl-c (Tyr700) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-Cbl-c (Tyr700) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cbl-c (Tyr700). Anti-Phospho-Cbl-c (Tyr700) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA. |
别名 | p-Cbl-c (Y700), p-Cbl-c (Tyr700), Cbl-c (p-Y700), Cbl-c (p-Tyr700) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:10000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | Cbl proto-oncogene(CBL) Homo sapiens This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016], |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human CBL around the phosphorylation site of Tyr700. AA range:666-715 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 120 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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