Anti-HE4 Antibody (3J765)

Name: Anti-HE4 Antibody (3J765)
Brand: TargetMol
SKU: TMAY-02394
Rating: 4.5 (1 reviews)

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产品编号 TMAY-02394

Anti-HE4 Antibody (3J765) 是一种 Mouse 抗体，靶向 HE4。Anti-HE4 Antibody (3J765) 可用于 ELISA(Cap)。

Anti-HE4 Antibody (3J765)

还可以

产品编号 TMAY-02394

Anti-HE4 Antibody (3J765) 是一种 Mouse 抗体，靶向 HE4。Anti-HE4 Antibody (3J765) 可用于 ELISA(Cap)。

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生物活性

产品描述	Anti-HE4 Antibody (3J765) is a Mouse antibody targeting HE4. Anti-HE4 Antibody (3J765) can be used in ELISA(Cap).
Ig Type	Monoclonal Mouse IgG1
克隆号	3J765
交叉反应	Human
应用	ELISA(Cap)
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HE4/WFDC2/WAP5 (rh HE4/WFDC2/WAP5; TMPY-01882; NP_006094.3; Met1-Phe124). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2 / HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2 / HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human HE4/WFDC2/WAP5 Protein (TMPY-01882)
抗原种属	Human
研究领域	Serine Proteases and Regulators

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.