PHS Protein, Human, Recombinant (His)

Synonyms: Pterin-4-α-Carbinolamine Dehydratase, Pterin-4-Alpha-Carbinolamine Dehydratase, Pterin Carbinolami, PHS, Phenylalanine Hydroxylase-Stimulating Protein, Dimerization Cofactor of HNF1, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-α, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha, DCoH, 4-α-Hydroxy-Tetrahydropterin Dehydratase, 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase

规格

价格

库存

数量

5 μg

¥ 693

2-4周

10 μg

¥ 1,170

2-4周

20 μg

¥ 1,860

2-4周

50 μg

¥ 3,470

2-4周

100 μg

¥ 4,930

2-4周

200 μg

¥ 7,350

2-4周

500 μg

¥ 12,100

2-4周

1 mg

¥ 17,300

2-4周

生物活性

产品描述	Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type D (HPABH4D). HPABH4D is characterized by the excretion of 7-substituted Pterins in the urine of affected patients.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type D (HPABH4D). HPABH4D is characterized by the excretion of 7-substituted Pterins in the urine of affected patients.
种属	Human
表达系统	E. coli
标签	N-6xHis
蛋白编号	P61457
氨基酸序列	Ala2-Thr104
蛋白构建	Ala2-Thr104
缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, pH 8.0.
别名	Pterin-4-α-Carbinolamine Dehydratase, Pterin-4-Alpha-Carbinolamine Dehydratase, Pterin Carbinolami, PHS, Phenylalanine Hydroxylase-Stimulating Protein, Dimerization Cofactor of HNF1, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-α, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha, DCoH, 4-α-Hydroxy-Tetrahydropterin Dehydratase, 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.

化学信息

分子量	14 KDa (reducing condition)

储存&溶解度

运输方式	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

PHS Protein, Human, Recombinant (His)

PHS Protein, Human, Recombinant (His)

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