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Anti-Olig-2/Oligo2 Antibody (5L16) 是一种 Rabbit 抗体,靶向 Olig-2/Oligo2。Anti-Olig-2/Oligo2 Antibody (5L16) 可用于 WB,IHC-P。
Anti-Olig-2/Oligo2 Antibody (5L16) 是一种 Rabbit 抗体,靶向 Olig-2/Oligo2。Anti-Olig-2/Oligo2 Antibody (5L16) 可用于 WB,IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
20 μL | ¥ 780 | 5日内发货 | |
100 μL | ¥ 2,294 | 5日内发货 |
产品描述 | Anti-Olig-2/Oligo2 Antibody (5L16) is a Rabbit antibody targeting Olig-2/Oligo2. Anti-Olig-2/Oligo2 Antibody (5L16) can be used in WB,IHC-P. |
别名 | RACK17, PRKCBP2, OLIGO2, Olig2, bHLHe19, BHLHB1 |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 5L16 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human olig-2 in human glioma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human olig-2 in human brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Anti-Olig-2 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Jurkat Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:32 kDa. -Observed band size:37 kDa |
应用 | WB,IHC-P |
推荐剂量 | WB: 1:500-1:2000; IHC-P: 1:100-1:500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, synthetic peptide corresponding to the N-terminus of the Human Olig-2. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Olig2, also known as Oligo2, is a basic helix-loop-helix transcription factor that is expressed in oligodendroglial tumors of the brain. Oligo2 is structurally similar to OLIG1. Both of them have non-overlapping developmental functions in patterning, neuron subtype specification, and the formation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Its over-expression inhibits neural progenitor proliferation through changes in potassium channel activity, thereby contributing to the reduced neuronal numbers and brain size in down syndrome. Olig2 may be a cause of a form of T-cell acute lymphoblastic leukemia. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide corresponding to the N-terminus of the Human Olig-2. |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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