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Anti-Prostasin/PRSS8 Antibody (9T600)

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Anti-Prostasin/PRSS8 Antibody (9T600)
产品编号 TMAY-00556
别名 protease, serine, 8

Anti-Prostasin/PRSS8 Antibody (9T600) 是一种 Rabbit 抗体，靶向 Prostasin/PRSS8。Anti-Prostasin/PRSS8 Antibody (9T600) 可用于 ELISA。

Anti-Prostasin/PRSS8 Antibody (9T600)
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Anti-Prostasin/PRSS8 Antibody (9T600)

Rating icon 还可以
Anti-Prostasin/PRSS8 Antibody (9T600)
产品编号 TMAY-00556 别名 protease, serine, 8

Anti-Prostasin/PRSS8 Antibody (9T600) 是一种 Rabbit 抗体，靶向 Prostasin/PRSS8。Anti-Prostasin/PRSS8 Antibody (9T600) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
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产品介绍

生物活性
产品描述
Anti-Prostasin/PRSS8 Antibody (9T600) is a Rabbit antibody targeting Prostasin/PRSS8. Anti-Prostasin/PRSS8 Antibody (9T600) can be used in ELISA.
别名protease, serine, 8
Ig Type
Rabbit IgG
克隆号
9T600
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Prostasin / PRSS8 (rh PRSS8; TMPY-00905; NP_002764.1; Ala 30-Arg 322).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from human seminal fluid and is highly expressed in prostate, lung, kidney, salivary gland and pancreas. Prostasin is expressed as a glycosyl-phosphatidylinositol (GPI)-anchored membrane protein in prostate epithelial cells, and also exists as a secreted proteolytic enzyme possibly via tryptic cleavage of its COOH-terminal hydrophobic domain. Prostasin is found to activate the epithelial sodium channel (ENaC) which is tightly regulated and is critical for maintaining salt and fluid balance in the lung and kidney in both normal and pathological conditions. Accordingly, prostasin has been proposed as a target for therapeutic inhibition in cystic fibrosis. Besides, prostasin inhibits prostate and breast cancer cell invasion in vitro, suggesting a functional role as a suppressor of tumor invasion, as well as a regulator of gene expression during inflammation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human PRSS8 protein (TMPY-00905)
抗原种属
Human
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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