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Anti-Prostasin/PRSS8 Antibody (9T600)
还可以产品编号 TMAY-00556
Anti-Prostasin/PRSS8 Antibody (9T600) 是一种 Rabbit 抗体，靶向 Prostasin/PRSS8。Anti-Prostasin/PRSS8 Antibody (9T600) 可用于 ELISA。
Anti-Prostasin/PRSS8 Antibody (9T600)
Anti-Prostasin/PRSS8 Antibody (9T600)
还可以产品编号 TMAY-00556
Anti-Prostasin/PRSS8 Antibody (9T600) 是一种 Rabbit 抗体，靶向 Prostasin/PRSS8。Anti-Prostasin/PRSS8 Antibody (9T600) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Prostasin/PRSS8 Antibody (9T600) is a Rabbit antibody targeting Prostasin/PRSS8. Anti-Prostasin/PRSS8 Antibody (9T600) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9T600 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Prostasin / PRSS8 (rh PRSS8; TMPY-00905; NP_002764.1; Ala 30-Arg 322). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from human seminal fluid and is highly expressed in prostate, lung, kidney, salivary gland and pancreas. Prostasin is expressed as a glycosyl-phosphatidylinositol (GPI)-anchored membrane protein in prostate epithelial cells, and also exists as a secreted proteolytic enzyme possibly via tryptic cleavage of its COOH-terminal hydrophobic domain. Prostasin is found to activate the epithelial sodium channel (ENaC) which is tightly regulated and is critical for maintaining salt and fluid balance in the lung and kidney in both normal and pathological conditions. Accordingly, prostasin has been proposed as a target for therapeutic inhibition in cystic fibrosis. Besides, prostasin inhibits prostate and breast cancer cell invasion in vitro, suggesting a functional role as a suppressor of tumor invasion, as well as a regulator of gene expression during inflammation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human PRSS8 protein (TMPY-00905) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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