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Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody

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产品编号 TMAC-02229

别名 p-Aconitase 1 (Ser138), p-Aconitase 1 (S138), Aconitase 1 (p-Ser138), Aconitase 1 (p-S138)

Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Aconitase 1 (Ser138)。Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 可用于 ELISA,ICC/IF,IHC-P。

Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody

Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
产品编号 TMAC-02229 别名 p-Aconitase 1 (Ser138), p-Aconitase 1 (S138), Aconitase 1 (p-Ser138), Aconitase 1 (p-S138)

Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Aconitase 1 (Ser138)。Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 可用于 ELISA,ICC/IF,IHC-P。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Aconitase 1 (Ser138). Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody can be used in ELISA,ICC/IF,IHC-P.
别名p-Aconitase 1 (Ser138), p-Aconitase 1 (S138), Aconitase 1 (p-Ser138), Aconitase 1 (p-S138)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
应用ELISAICC/IFIHC-P
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:10000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景aconitase 1(ACO1) Homo sapiens The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human IREB1 around the phosphorylation site of Ser138. AA range:106-155
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 98 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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