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别名 p-Aconitase 1 (Ser138), p-Aconitase 1 (S138), Aconitase 1 (p-Ser138), Aconitase 1 (p-S138)
Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Aconitase 1 (Ser138)。Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 可用于 ELISA,ICC/IF,IHC-P。
Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Aconitase 1 (Ser138)。Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody 可用于 ELISA,ICC/IF,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,240 | 5日内发货 |
| 产品描述 | Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Aconitase 1 (Ser138). Anti-Phospho-Aconitase 1 (Ser138) Polyclonal Antibody can be used in ELISA,ICC/IF,IHC-P. |
| 别名 | p-Aconitase 1 (Ser138), p-Aconitase 1 (S138), Aconitase 1 (p-Ser138), Aconitase 1 (p-S138) |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 应用 | ELISAICC/IFIHC-P |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 性状 | Liquid |
| 缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 研究背景 | aconitase 1(ACO1) Homo sapiens The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | A synthesized phosphopeptide: human IREB1 around the phosphorylation site of Ser138. AA range:106-155 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 98 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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