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Anti-WHSC2 Antibody (5N717) 是一种 Mouse 抗体,靶向 WHSC2。Anti-WHSC2 Antibody (5N717) 可用于 WB,ICC,IHC,FCM。
Anti-WHSC2 Antibody (5N717) 是一种 Mouse 抗体,靶向 WHSC2。Anti-WHSC2 Antibody (5N717) 可用于 WB,ICC,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,980 | 5日内发货 | |
100 μL | ¥ 2,990 | 5日内发货 |
产品描述 | Anti-WHSC2 Antibody (5N717) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Antibody (5N717) can be used in WB,ICC,IHC,FCM. |
别名 | Wolf-Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2, WHSC 2, P/OKcl15, P/OKcl.15, NELFA_HUMAN, NELF-A, NELFA, NELF A, Negative elongation factor polypeptide A, Negative elongation factor A, FLJ25112, FLJ10442 |
交叉反应 | Human,Rat |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:100-200; ICC: 1:50-200; FCM: 1:100-200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | NELF-A, for negative elongation factor A, is a protein factor required for DRB-sensitive transcription. NELF-A is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b (P-TEFb) and negative transcription elongation factors, DSIF and NELF. DSIF and NELF act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. DSIF/NELF inhibition of transcription is prevented by P-TEFb in cooperation with FACT. NELF-A is also known as WHSC2 (Wolf-Hirschhorn syndrome candidate 2). Wolf-Hirschhorn syndrome is a multiple malformation syndrome characterized by mental and developmental defects resulting from a hemizygous deletion of the distal short arm of chromosome 4 (4p16.3). The human NELF-A gene maps to chromosome 4p16.3 and encodes a 528 amino acid protein that is expressed in endothelial cells. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 57 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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