PROTAC-Linker Conjugates for PAC

PROTAC-Linker Conjugates for PAC are composed of PROTAC and bifunctional or multifunctional linkers, which can be further linked to antibodies through the linkers to form PAC. The antibodies in PAC can target specific antigens on the cell membrane surface, helping PROTAC effectively locate on the cell membrane surface and thereby enter the cell through cytotoxic effects.

筛选首页信号通路PROTACPROTAC-Linker Conjugates for PAC

MC-GGFG-DX8951
MC-GGFG-Exatecan
T160241600418-29-8
MC-GGFG-DX8951(MC-GGFG-Exatecan)是一种抗体偶联药物（ADC）的药物-连接子偶联物（drug-linker conjugate）.由强效的DNA拓扑异构酶I抑制剂DX8951、连接子MC和可被蛋白酶降解（cleavable）的肽链GGFG组成，具有抗肿瘤的潜力。
Drug-Linker Conjugates for ADC PROTAC-Linker Conjugates for PAC PROTAC-Linker Conjugates for PAC Topoisomerase
- ¥ 392
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PROTAC BRD4 degrader for PAC-1
T18603
PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective proteolysis of PAC-1.
PROTAC-Linker Conjugates for PAC PROTAC-Linker Conjugates for PAC
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PAC
T185142158322-33-7
PAC is a chemical conjugate consisting of an ADCs linker and PROTACs linked to an antibody. When PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) in comparison to PROTAC alone.
Estrogen Receptor/ERR PROTAC-Linker Conjugates for PAC PROTAC-Linker Conjugates for PAC
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PROTAC BTK Degrader-8
T208958
PROTACBTK Degrader-8 (compound 3) 是一种高效的 PROTACBTK 降解剂，配备接头，可与 ADC 抗体结合形成 PAC。
BTK PROTAC-Linker Conjugates for PAC PROTAC-Linker Conjugates for PAC
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