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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DR5 Polyclonal Antibody

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货号 TMAB-05312

Anti-DR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DR5。Anti-DR5 Polyclonal Antibody 可用于 WB,ICC/IF。

Anti-DR5 Polyclonal Antibody

Anti-DR5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05312

Anti-DR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DR5。Anti-DR5 Polyclonal Antibody 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-DR5 Polyclonal Antibody is a Rabbit antibody targeting DR5. Anti-DR5 Polyclonal Antibody can be used in WB,ICC/IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane
组织特异性Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
抗原信息
免疫原
KLH conjugated synthetic peptide: rat DR5
抗原种属
Rat
基因名称
TNFRSF10B
基因ID
364420
蛋白名称
Tumor necrosis factor receptor superfamily member 10B
功能
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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