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The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 76.3 kDa and the accession number is XP_005545315.1.
别名 TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 76.3 kDa and the accession number is XP_005545315.1.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 246 | 6-8日内发货 | |
| 10 μg | ¥ 383 | 6-8日内发货 | |
| 20 μg | ¥ 616 | 5日内发货 | |
| 50 μg | ¥ 1,190 | 5日内发货 | |
| 100 μg | ¥ 1,990 | 5日内发货 | |
| 200 μg | ¥ 3,590 | 5日内发货 | |
| 500 μg | ¥ 8,000 | 5日内发货 |
| 产品描述 | The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 76.3 kDa and the accession number is XP_005545315.1. |
| 生物活性 | Immobilized Cynomolgus Transferrin R, His Tag at 2 μg/mL (100 μL/well) on the plate. Dose response curve for Biotinylated Human Transferrin, His Avi Tag with the EC50 of 12.9 ng/mL determined by ELISA.(QC Test) |
| 研究背景 | The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. |
| 种属 | Cynomolgus |
| 表达系统 | HEK293 Cells |
| 标签 | N-His |
| 蛋白编号 | XP_005545315.1 |
| 蛋白构建 | Cys89-Phe760 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71 |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 76.3 kDa (predicted). Due to glycosylation, the protein migrates to 78-80 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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