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HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated

HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated

产品编号 TMPJ-00413
别名: Proto-oncogene-like protein c-ErbB-3, HER3, ERBB3, Tyrosine kinase-type cell surface receptor HER3

HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 90-120 KDa and the accession number is P21860.

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HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated
规格 价格/CNY 货期 数量
20 μg ¥ 2,260 5日内发货
100 μg ¥ 6,130 5日内发货
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产品目录号及名称: HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated (TMPJ-00413)
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产品描述 HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 90-120 KDa and the accession number is P21860.
种属 Human
表达系统 HEK293 Cells
标签 C-6xHis-Avi
蛋白编号 P21860
别名 Proto-oncogene-like protein c-ErbB-3, HER3, ERBB3, Tyrosine kinase-type cell surface receptor HER3
氨基酸序列 Ser20-Thr643
蛋白构建 Ser20-Thr643
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 90-120 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belongs to the protein kinase superfamily,tyr protein kinase family and EGF receptor subfamily.It contains 1 protein kinase domain and it is expressed in Epithelial tissues and brain. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity.

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Keywords

HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated Proto-oncogene-like protein c-ErbB-3 HER3 HER 3 ERBB 3 ERBB3 Tyrosine kinase-type cell surface receptor HER3 HER-3 ERBB-3 recombinant recombinant-proteins proteins protein

 

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