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Anti-GRK6 Antibody (5G602)

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货号 TMAB-06785

Anti-GRK6 Antibody (5G602) 是一种 Rabbit 抗体,靶向 GRK6。Anti-GRK6 Antibody (5G602) 可用于 WB。

Anti-GRK6 Antibody (5G602)

Anti-GRK6 Antibody (5G602)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06785

Anti-GRK6 Antibody (5G602) 是一种 Rabbit 抗体,靶向 GRK6。Anti-GRK6 Antibody (5G602) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-GRK6 Antibody (5G602) is a Rabbit antibody targeting GRK6. Anti-GRK6 Antibody (5G602) can be used in WB.
Ig Type
IgG
克隆号
5G602
反应种属
Human,Mouse
应用WB
推荐剂量
WB: 1:1000-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Lipid-anchor.
组织特异性Widely expressed.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
抗原信息
免疫原
A synthesized peptide: human GRK6
抗原种属
Human
基因名称
GRK6
基因ID
蛋白名称
G protein-coupled receptor kinase 6
Uniprot ID
功能
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamin receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
化学信息
分子量Theoretical: 66 kDa. Actual: 66 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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