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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Claudin 17 Polyclonal Antibody

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货号 TMAB-04421

Anti-Claudin 17 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin 17。Anti-Claudin 17 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Claudin 17 Polyclonal Antibody

Anti-Claudin 17 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04421

Anti-Claudin 17 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin 17。Anti-Claudin 17 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-Claudin 17 Polyclonal Antibody is a Rabbit antibody targeting Claudin 17. Anti-Claudin 17 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Integral membrane protein. Tight junctions.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecules (JAMs). Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Mammalian claudin-17 and claudin-8 may be the result of a gene duplication. Claudin-17 is expressed in stratum granulosum of the epidermis and infundibulum and predominantly localizes to the plasma membrane.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Claudin 17
抗原种属
Human
基因名称
CLDN17
基因ID
26285
蛋白名称
Claudin-17
Uniprot ID
P56750
功能
Claudin proteins are a family of transmembrane proteins associated with tight junctions, and different tissues exhibit different Claudin composition. There are 18 homolgs present in humans, and mutations in any of these proteins cause a variety of human disease, this indicates their physiological importance. CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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