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Anti-LRP5L Polyclonal Antibody

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货号 TMAB-08402

Anti-LRP5L Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRP5L。Anti-LRP5L Polyclonal Antibody 可用于 WB。

Anti-LRP5L Polyclonal Antibody

Anti-LRP5L Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08402

Anti-LRP5L Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRP5L。Anti-LRP5L Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-LRP5L Polyclonal Antibody is a Rabbit antibody targeting LRP5L. Anti-LRP5L Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LRP5L
抗原种属
Human
基因名称
LRP5L
基因ID
蛋白名称
Low-density lipoprotein receptor-related protein 5-like protein
Uniprot ID
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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