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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD19 Antibody (9T48)

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货号 TMAB-03888

Anti-CD19 Antibody (9T48) 是一种 Rabbit 抗体，靶向 CD19。Anti-CD19 Antibody (9T48) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CD19 Antibody (9T48)

Anti-CD19 Antibody (9T48)

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Rating icon 还可以
货号 TMAB-03888

Anti-CD19 Antibody (9T48) 是一种 Rabbit 抗体，靶向 CD19。Anti-CD19 Antibody (9T48) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD19 Antibody (9T48) is a Rabbit antibody targeting CD19. Anti-CD19 Antibody (9T48) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
9T48
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the immunoglobulin gene superfamily. Expression of this cell surface protein is restricted to B cell lymphocytes. This protein is a reliable marker for pre-B cells but its expression diminishes during terminal B cell differentiation in antibody secreting plasma cells. The protein has two N-terminal extracellular Ig-like domains separated by a non-Ig-like domain, a hydrophobic transmembrane domain, and a large C-terminal cytoplasmic domain. This protein forms a complex with several membrane proteins including complement receptor type 2 (CD21) and tetraspanin (CD81) and this complex reduces the threshold for antigen-initiated B cell activation. Activation of this B-cell antigen receptor complex activates the phosphatidylinositol 3-kinase signalling pathway and the subsequent release of intracellular stores of calcium ions. This protein is a target of chimeric antigen receptor (CAR) T-cells used in the treatment of lymphoblastic leukemia. Mutations in this gene are associated with the disease common variable immunodeficiency 3 (CVID3) which results in a failure of B-cell differentiation and impaired secretion of immunoglobulins. CVID3 is characterized by hypogammaglobulinemia, an inability to mount an antibody response to antigen, and recurrent bacterial infections. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2020]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD19
抗原种属
Human
基因名称
CD19
基因ID
930
蛋白名称
B-lymphocyte antigen CD19
Uniprot ID
P15391
功能
Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
化学信息
分子量Theoretical: 59 kDa. Actual: 95 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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