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Anti-Transferrin Antibody (1J807)

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产品编号 TMAY-01472

Anti-Transferrin Antibody (1J807) 是一种 Rabbit 抗体,靶向 Transferrin。Anti-Transferrin Antibody (1J807) 可用于 ELISA。

Anti-Transferrin Antibody (1J807)

Anti-Transferrin Antibody (1J807)

Rating icon 还可以
产品编号 TMAY-01472

Anti-Transferrin Antibody (1J807) 是一种 Rabbit 抗体,靶向 Transferrin。Anti-Transferrin Antibody (1J807) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-Transferrin Antibody (1J807) is a Rabbit antibody targeting Transferrin. Anti-Transferrin Antibody (1J807) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
1J807
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Transferrin / TF (rh Transferrin / TF; TMPY-01279; NP_001054.1; Met 1-Pro 698).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of Transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte / pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. Transferrins are iron binding transport proteins that bind Fe3+ion in association with the binding of an anion, usually bicarbonate. This transferrin binds only one Fe3+ion per protein molecule. Transports iron ions from the hemolymph into the eggs during the vitellogenic stage. Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. When a transferrin loaded with iron encounters with a transferring receptor on cell surface, transferring binds to it and, as a consequence, is transported into the cell in a visicle by receptor-mediated endocytosis. The PH is reduced by hydrogen iron pumps. The lower pH causes transferrin to release its iron ions. The receptor is then transported through the endocytic cycle back to the cell surface, ready for another round of iron uptake. Each transferrin molecule has the ability to carry two iron ions in the ferric form.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human Transferrin / TF protein (TMPY-01279)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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