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TargetMol | Compound Library

抗HIV筛选化合物库

Anti-HIV Screening Libraries

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产品编号 LF1300

抗HIV 筛选库包含16800种化合物。联合抗逆转录病毒疗法是降低艾滋病病毒感染者病毒载量的关键方法。它将几种具有不同活性类型的药物组合到艾滋病毒治疗方案中,抑制感染并阻止其进展为艾滋病。多药物策略多年来变得非常有效和可行,成功提高了HIV 阳性个体的生活质量。 大约有50种获批的HIV 药物可作为个性化治疗方案的组成部分。根据病毒靶点和活性物质的不同,它们分为七个主要的药物类别。不同的药物在HIV 生命周期的不同阶段起作用:有些药物可以阻止病毒进入免疫系统细胞;其他药物能够阻断HIV 复制所需的酶 - 逆转录酶、蛋白酶和整合酶。这种选择的多样性源于30多年来的密集研究努力。然而,通过控制HIV 作为一种慢性疾病的能力只是完全康复的一步。治愈仍然是医学上重大的挑战之一,这促使人们不断寻找创新的抗HIV 药物和治疗策略。针对这一迫切需求,Life Chemicals 推出了一套专有的抗HIV 筛选库,为抗逆转录病毒研究做出贡献。通过2D 指纹相似性方法设计,该库包含超过16,800种具有强效抗逆转录病毒活性的药物样式筛选化合物。 国内备有现货产品,包含4221种化合物,货期更短,性价比更高,欢迎咨询!

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产品编号 LF1300

抗HIV筛选化合物库

规格

  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

Product Description Product Description

Around 50 approved HIV medicines may serve as components of a personalized treatment regimen. Depending on a viral target and active substance, they form seven main drug classes. Various medications operate at different stages of the HIV life cycle: some of them prevent the virus from entering the immune system cells; others are able to block enzymes that HIV needs to replicate – reverse transcriptase, protease, and integrase. This variability of options stems from over 30 years of intense research efforts. However, the resulting ability to control HIV as a chronic disease is just a step towards complete recovery. The cure continues to be one of the greatest medical challenges, which motivates a permanent search for innovative anti-HIV drugs and treatment strategies. In response to this acute need, Life Chemicals contributes to antiretroviral research with a proprietary set of Anti-HIV Screening Libraries. Designed with a 2D fingerprint similarity approach, this Library contains over 16,800 drug-like screening compounds with potent antiretroviral activity.

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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