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Anti-KRT6A Antibody (4G523)
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产品编号 TMAC-01092
别名 Type-II keratin Kb6, type II cytoskeletal 6A, KRT 6A, Keratin-6A, Keratin, K6A KRT6D, K6A, Cytokeratin-6D, Cytokeratin-6A, CK-6D, CK-6A
Anti-KRT6A Antibody (4G523) 是一种 Rabbit 抗体，靶向 KRT6A。Anti-KRT6A Antibody (4G523) 可用于 WB,ICC/IF,IHC。
Anti-KRT6A Antibody (4G523)
Anti-KRT6A Antibody (4G523)
还可以产品编号 TMAC-01092 别名 Type-II keratin Kb6, type II cytoskeletal 6A, KRT 6A, Keratin-6A, Keratin, K6A KRT6D, K6A, Cytokeratin-6D, Cytokeratin-6A, CK-6D, CK-6A
Anti-KRT6A Antibody (4G523) 是一种 Rabbit 抗体，靶向 KRT6A。Anti-KRT6A Antibody (4G523) 可用于 WB,ICC/IF,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-KRT6A Antibody (4G523) is a Rabbit antibody targeting KRT6A. Anti-KRT6A Antibody (4G523) can be used in WB,ICC/IF,IHC. |
| 别名 | Type-II keratin Kb6, type II cytoskeletal 6A, KRT 6A, Keratin-6A, Keratin, K6A KRT6D, K6A, Cytokeratin-6D, Cytokeratin-6A, CK-6D, CK-6A |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of Cytokeratin 6 on human skin lysates using anti-Cytokeratin 6 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 6 antibody. Counter stained with hematoxylin. 3. ICC staining Cytokeratin 6 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins, which are useful markers of tissue differentiation, also aid in the characterization of malignant tumors. IL-1 and TNFα induce transcription of cytokeratin 6 in epidermal keratinocytes via the C/EBP β transcription factor. In humans, multiple isoforms of cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 60 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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