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Anti-IL-12B Antibody (6O329) 是一种 Rabbit 抗体,靶向 IL-12B。Anti-IL-12B Antibody (6O329) 可用于 ELISA。
Anti-IL-12B Antibody (6O329) 是一种 Rabbit 抗体,靶向 IL-12B。Anti-IL-12B Antibody (6O329) 可用于 ELISA。
产品描述 | Anti-IL-12B Antibody (6O329) is a Rabbit antibody targeting IL-12B. Anti-IL-12B Antibody (6O329) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6O329 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-12 p40/IL12B (rM IL-12 p40/IL12B; TMPY-03516; P43432; Met1-Ser335). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine is important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. IL12B/IL-12B associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine that functions in innate and adaptive immunity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse IL-12 p40/IL12B Protein (TMPY-03516) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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