Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 4,440 | 5日内发货 | ||
500 μg | ¥ 17,800 | 5日内发货 | ||
1 mg | ¥ 29,600 | 5日内发货 |
生物活性 | Immobilized Canine GDF15, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 48.3ng/ml determined by ELISA. |
产品描述 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6. |
种属 | Canine |
表达系统 | E. coli |
标签 | N-His |
蛋白编号 | A0A8C0TNP6 |
别名 | GDF15, MIC1, MIC-1, PLAB, GDF-15, PDF, PTGFB, PTGF-beta, RG-1, Placental TGF-β, PTGF-β, PTGFBPTGF-beta, NAG-1, Placental TGF-beta, PTGFBPTGF-β |
蛋白构建 | Ala197-Val307 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | 13.12 kDa (predicted). The protein migrates to 15-20 kDa under reduced (R) condition and 23-26 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM HAc (pH 2.9). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
复溶方法 | Reconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |
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GDF-15 Protein, Canine, Recombinant (His) GDF15 MIC1 MIC-1 RG 1 NAG1 PLAB PTGFBPTGF-b RG1 NAG 1 GDF-15 PDF PTGFB PTGF-b PTGF-beta RG-1 Placental TGF-β PTGF-β Placental TGF-b PTGFBPTGF-beta NAG-1 Placental TGF-beta GDF 15 PTGFBPTGF-β MIC 1 recombinant recombinant-proteins proteins protein