CD39 Protein, Mouse, Recombinant (His)

CD39 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is P55772.

规格	价格/CNY		数量
50 μg	￥ 1,980	现货
100 μg	￥ 3,510	5日内发货
200 μg	￥ 6,230	5日内发货
500 μg	￥ 13,200	5日内发货

规格

价格/CNY

货期

数量

50 μg

￥ 1,980

现货

100 μg

￥ 3,510

5日内发货

200 μg

￥ 6,230

5日内发货

500 μg

￥ 13,200

5日内发货

生物活性	Measured by its ability to hydrolyze the 5’phosphategroups from the substrate adenosine 5’triphosphate(ATP). The specific activity is > 25,000 pmoles/min/μg.
产品描述	CD39 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is P55772.

种属	Mouse
表达系统	Baculovirus Insect Cells
标签	C-His
蛋白编号	P55772
别名	NTPDase-1, AA408691, ectonucleoside triphosphate diphosphohydrolase 1, 2610206B08Rik, Cd39
蛋白构建	The Mouse ENTPD1 (P55772) extracellular domain (Thr 38-Ile 478) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
蛋白纯度	> 95 % as determined by SDS-PAGE
分子量	51 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% gly.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.